Shortly after Mr. Reavis settled, Mr. Benjamin Prigmore and his family arrived. The following year the Rev. Isham Reavis, a brother to Edward and an old school Baptish minister came to the area. In 1820, they were joined by Mr. Duke Prigmore.
Other early arrivals included John and Robert Owens, Issac Parsons and sons, John Logston, Jacob Spotts, James Reid, Thomas Reid, Thomas Miller, Felix Bradly, Issac VanMeter, John L. Baily, Issac King, William Kincaid, John and Robert Montgomery, Edward Armentrout and John McAllister.
The town now known as Sweet Springs was first settled May 2, 1835 by Asa Pennington from Kentucky, when he purchased forty acres of land lying South of what is now Main Street. Mr. Pennington built a grist mill and a saw mill on Davis Creak. The following year he built a log cabin with a blacksmith shop annex and named his settlement Clayville.
In 1836, Kentuckian, Mr. John Berry, purchased forty acres in the area. In 1837, Mr. James Fitzpatrick purchased eighty acres which comprise the present business district of Sweet Springs. Mr. Fitzpatrick then built a house and a dry goods store on Main Street.